Best Practice & Research Clinical Endocrinology & Metabolism
Volume 22, Issue 6 , Pages 1039-1046, December 2008

Serum thyroglobulin determination in thyroid cancer patients

Department of Nuclear Medicine and Endocrine Oncology, Institut Gustave Roussy, University Paris Sud-XI, rue Camille Desmoulins, 94805 Villejuif Cédex, France

Serum thyroglobulin determination plays a central role, in combination with neck ultrasonography, in the follow-up of thyroid cancer patients. Its specificity is improved by thyroid remnant ablation, and its sensitivity is optimal following prolonged withdrawal or stimulation with recombinant human thyroid-stimulating hormone (TSH). Modern methods with an improved functional sensitivity may facilitate its use during follow-up.

Key words: thyroglobulin, thyroid cancer, follow-up, neck ultrasonography, recombinant human TSH

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PII: S1521-690X(08)00115-2

doi:10.1016/j.beem.2008.09.015

Best Practice & Research Clinical Endocrinology & Metabolism
Volume 22, Issue 6 , Pages 1039-1046, December 2008

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