Best Practice & Research Clinical Endocrinology & Metabolism
Volume 22, Issue 5 , Pages 885-900, October 2008

Health economics of osteoporosis

  • Fredrik Borgström, PhD (Adjunct Lecturer)

      Affiliations

    • Corresponding Author InformationCorresponding author. Tel.: +46 8 545 28 544; Fax: +46 8 545 28 549.

Medical Management Centre, Karolinska Institutet, 171 77 Stockholm, Sweden

i3 Innovus, Vasagatan 38 2 tr, SE-111 20 Stockholm, Sweden

WHO Collaborating Centre for Metabolic Bone Diseases, University of Sheffield Medical School, Beech Hill Road, Sheffield S10 2RX, UK

Rather than reviewing the many studies of cost effectiveness in osteoporosis, this paper reviews the principles of cost-effectiveness analysis and the gaps in our knowledge that are required to improve such analyses in osteoporosis. These include more information on the cost of fractures and their consequences on health states, particularly on an international basis. New developments include the incorporation of adherence into models, the use of the FRAX™ tool to assess cost-effectiveness in individuals with any combination of risk factors for fracture, and the setting of intervention thresholds based on cost-effectiveness.

Key words: osteoporosis, fractures, health economics, cost-effectiveness

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PII: S1521-690X(08)00083-3

doi:10.1016/j.beem.2008.07.005

Best Practice & Research Clinical Endocrinology & Metabolism
Volume 22, Issue 5 , Pages 885-900, October 2008

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