Best Practice & Research Clinical Endocrinology & Metabolism
Volume 21, Issue 1 , Pages 145-162, March 2007

Biotherapy

  • U. Plöckinger, MD (Senior Consultant, Interdisziplinary Centre of Metabolism:Endocrinology, Diabetes and Metabolism)

      Affiliations

    • Corresponding Author InformationCorresponding author. Tel.: +49 30 450 553 552; Fax: +49 30 450 7553 552.
  • B. Wiedenmann, MD (Professor of Gastroenterology and Head of the Department of Hepatology and Gastroenterology)

Interdisziplinäres Stoffwechsel-Centrum, Med. Klinik m. S. Hepatologie und Gastroenterologie, Charité-Universitätsmedizin Berlin, Campus Virchow-Klinikum, Augustenburger Platz 1, 13353 Berlin, Germany

Med. Klinik m. S. Hepatologie und Gastroenterologie, Charité-Universitätsmedizin Berlin, Campus Virchow-Klinikum, Augustenburger Platz 1, 13353 Berlin, Germany

This review gives an introduction to the classification and staging of neuroendocrine tumors, as the prognostic implications of these classifications influence therapeutic decisions. The indications for biotherapy are given, together with a short update on the mechanism of somatostatin analogs and interferon-α therapy. This is followed by an in-depth description of the use of biotherapy, its results with respect to symptomatic and antiproliferative treatment, as well as its side-effects.

Key words: neuroendocrine tumor, biotherapy, somatostatin analog, interferon

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PII: S1521-690X(07)00003-6

doi:10.1016/j.beem.2007.01.002

Best Practice & Research Clinical Endocrinology & Metabolism
Volume 21, Issue 1 , Pages 145-162, March 2007

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